Abstract 5883: Role of major facilitative folate transporters SLC19A1 and SLC46A1 in cyclic dinucleotide transport and STING signaling
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DOI: 10.1158/1538-7445.am2024-5883
Abstract: Activation of stimulator of interferon genes (STING) activates the transcription factor pIRF3, promoting gene transcription encoding type I interferons including IFNβ that stimulate broader immune responses. Targeting the STING pathway for cancer is especially compelling… read more here.
Keywords: transport; tet rfc; adu s100; pcft ... See more keywords