Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity
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DOI: 10.3389/fimmu.2024.1380641
Abstract: Recent studies have demonstrated a role for Ten-Eleven Translocation-2 (TET2), an epigenetic modulator, in regulating germinal center formation and plasma cell differentiation in B-2 cells, yet the role of TET2 in regulating B-1 cells is… read more here.
Keywords: tet2 mice; igm production; tet2 increases; tet2 ... See more keywords