Articles with "tet2 missense" as a keyword



Photo by timmossholder from unsplash

TET2 missense variants in human neoplasia. A proposal of structural and functional classification

Sign Up to like & get
recommendations!
Published in 2019 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.772

Abstract: The human TET2 gene plays a pivotal role in the epigenetic regulation of normal and malignant hematopoiesis. Somatic TET2 mutations have been repeatedly identified in ageā€related clonal hematopoiesis and in myeloid neoplasms ranging from acute… read more here.

Keywords: missense variants; tet2; structural functional; variants human ... See more keywords