Intramuscular tetanus neurotoxin reverses muscle atrophy: a randomized controlled trial in dogs with spinal cord injury.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12836
Abstract: BACKGROUND Motor symptoms of spinal cord injury (SCI) considerably impair quality of life and are associated with a high risk of secondary diseases. So far, no pharmacological treatment is available for these symptoms. Therefore, we… read more here.
Keywords: tetanus neurotoxin; muscle; muscle atrophy; reverses muscle ... See more keywords
Facial neuromuscular junctions and brainstem nuclei are the target of tetanus neurotoxin in cephalic tetanus.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.166978
Abstract: Cephalic tetanus (CT) is a severe form of tetanus that follows head wounds and the intoxication of cranial nerves by tetanus neurotoxin (TeNT). Hallmarks of CT are cerebral palsy, which anticipates the typical spastic paralysis… read more here.
Keywords: brainstem nuclei; neuromuscular junctions; cephalic tetanus; tetanus ... See more keywords
High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15040239
Abstract: Tetanus is an acute, fatal disease caused by exotoxins released from Clostridium tetani during infections. A protective humoral immune response can be induced by vaccinations with pediatric and booster combinatorial vaccines that contain inactivated tetanus… read more here.
Keywords: throughput igg; vaccine; high throughput; tent ... See more keywords