Inactivated tetanus as an immunological smokescreen: A major step towards harnessing tetanus-based therapeutics.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.09.008
Abstract: BACKGROUND AND PURPOSE Tetanus neurotoxin has many potential therapeutic applications, due to its ability to increase localised muscle tone when injected directly into a muscle. It is a closely related molecule to botulinum neurotoxin (most… read more here.
Keywords: major step; based therapeutics; tetanus toxin; toxin ... See more keywords
Neuroprotective Effects of C-terminal Domain of Tetanus Toxin on Rat Brain Against Motorneuron Damages After Experimental Spinal Cord Injury
Sign Up to like & getrecommendations! Published in 2018 at "SPINE"
DOI: 10.1097/brs.0000000000002357
Abstract: Study Design. Experimental animal study investigating the efficacy of C-terminal domain of tetanus toxin application as neuroprotective effects on rat brain in a model of spinal cord injury (SCI). Objective. The aim of the present… read more here.
Keywords: domain tetanus; terminal domain; spinal cord; tetanus toxin ... See more keywords
Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060756
Abstract: Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In parallel, current emphasis in the drug discovery field is… read more here.
Keywords: tetanus toxin; toxin fragment; drug discovery;