Preclinical development of the quadrivalent meningococcal (ACYW) tetanus toxoid conjugate vaccine, MenQuadfi®
Sign Up to like & getrecommendations! Published in 2022 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-022-10050-2
Abstract: Bacterial capsular polysaccharide vaccines are generally poorly immunogenic in infants and older adults. The immunogenicity of capsular polysaccharide vaccines can be improved by conjugating them to immunogenic carrier proteins. One of the most recently licensed… read more here.
Keywords: tetanus toxoid; development; conjugate; conjugate vaccine ... See more keywords
T‐cell–mediated immune response to pneumococcal conjugate vaccine (PCV‐13) and tetanus toxoid vaccine in patients with moderate‐to‐severe psoriasis during tofacitinib treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2017.09.076
Abstract: Background: Psoriasis is often treated with immunomodulatory therapies that can affect the immune response to common antigens. Tofacitinib is an oral Janus kinase inhibitor. Objective: To characterize the effect of long‐term exposure to tofacitinib 10… read more here.
Keywords: tetanus toxoid; pcv; psoriasis; vaccine ... See more keywords
Tetanus: remember to vaccinate
Sign Up to like & getrecommendations! Published in 2019 at "The Lancet"
DOI: 10.1016/s0140-6736(19)31137-7
Abstract: An 80-year-old Japanese man attended our hospital with a 3-day history of stiffness in his jaw and difficulty moving his right arm. He had no history of ever travelling abroad, but he did have a… read more here.
Keywords: tetanus; tetanus toxoid; right hand; per 100 ... See more keywords
Homogeneous Binary Visual and Fluorescence Detection of Tetanus Toxoid in Clinical Samples Based on Enzyme-Free Parallel Hybrid Chain Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c04818
Abstract: Here, we report a simple aptamer-based toxoid test with both fluorescence and binary visual readouts. This test is established based on our recent finding that CdTe quantum dots could differentiate DNA templated Cu NPs from… read more here.
Keywords: tetanus toxoid; reaction; fluorescence; detection ... See more keywords
A cell-based in vitro assay for testing of immunological integrity of Tetanus toxoid vaccine antigen
Sign Up to like & getrecommendations! Published in 2021 at "NPJ Vaccines"
DOI: 10.1038/s41541-021-00344-1
Abstract: Vaccines containing inactivated toxins confer protection by eliciting a neutralizing antibody response against bacterial toxins such as tetanus and diphtheria. At present, release of tetanus toxoid (TT) and diphtheria toxoid (DT)-containing vaccines relies on in… read more here.
Keywords: vitro assay; tetanus toxoid; vaccine antigen; vaccine ... See more keywords
Immunoadjuvant potential of cross-linked dextran microspheres mixed with chitosan nanospheres encapsulated with tetanus toxoid
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2016.1257032
Abstract: Abstract Context: Nasal mucosa is a desirable route for mucosal vaccine delivery. Mucosal co-administration of chitosan nanoparticles with absorption enhancers such as cross-linked dextran microspheres (CDM, Sephadex®) is a promising antigen delivery system. Objective: In… read more here.
Keywords: cht nps; cross linked; tetanus toxoid; linked dextran ... See more keywords
Seroefficacy of Vi Polysaccharide–Tetanus Toxoid Typhoid Conjugate Vaccine (Typbar TCV)
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/cix1145
Abstract: Background Salmonella Typhi is the major cause of enteric fever in lower-income countries. New conjugate vaccines show promise as public health interventions, but there are no efficacy data available from endemic areas. Methods Data were… read more here.
Keywords: polysaccharide tetanus; aged years; conjugate; tetanus toxoid ... See more keywords
Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abc1600
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment. Here, we present a microbial-based immunotherapeutic treatment for selective delivery of an… read more here.
Keywords: tetanus toxoid; toxoid protein; tumor cells; mice ... See more keywords
Prevalence and predictors of taking tetanus toxoid vaccine in pregnancy: a cross-sectional study of 8,722 women in Sierra Leone
Sign Up to like & getrecommendations! Published in 2020 at "BMC Public Health"
DOI: 10.1186/s12889-020-08985-y
Abstract: Background Immunization of women during pregnancy to protect them and their infants against tetanus, pertussis and influenza is recommended by the World health Organization (WHO). However, there is limited information about the coverage rate and… read more here.
Keywords: pregnancy; immunization; study; tetanus toxoid ... See more keywords
Tetanus toxoid pre-conditioning in recurrent glioblastoma treated with dendritic cell immunotherapy is associated to CD8+ T cell response.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e14053
Abstract: e14053Background: Recurrent glioblastoma (GBM) are highly aggressive tumors allowing 6-8 month survival. Recent data suggested that tetanus/ diphtheria toxoid (Td) preconditioning could increase de... read more here.
Keywords: recurrent glioblastoma; cell; tetanus toxoid;
Prevalence of protective tetanus antibodies and immunological response following tetanus toxoid vaccination among men seeking medical circumcision services in Uganda
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DOI: 10.1371/journal.pone.0209167
Abstract: Introduction Tetanus infection associated with men who had male circumcision has been reported in East Africa, suggesting a need for tetanus toxoid-containing vaccines (TTCV). Objective To determine the prevalence of tetanus toxoid antibodies following vaccination… read more here.
Keywords: immunological response; tetanus toxoid; circumcision; day ... See more keywords