Dysferlin-deficient myotubes show tethering of different membrane compartments characterized by TMEM16E and DHPRα.
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DOI: 10.1016/j.bbrc.2020.06.079
Abstract: TMEM16E deficiency has been shown to be responsible for human limb-girdle muscular dystrophy LGMD2L. We found that endogenous TMEM16E co-localized with caveolin-3 at cytoplasmic vesicular compartments in a myotube from C2C12 cells (C2C12 myotube) without forming… read more here.
Keywords: dysferlin deficient; tethering different; membrane compartments; membrane ... See more keywords