Articles with "tetra substituted" as a keyword



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A facile on-bead method for fully symmetric tetra-substituted DOTA derivatizations using peptoid moieties.

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Published in 2019 at "Biopolymers"

DOI: 10.1002/bip.23249

Abstract: The metal-chelated 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) has made a significant impact on the field of diagnostic imaging. This imaging mechanism is largely dependent on the four side arm functionalities around the DOTA scaffold. We previously demonstrated… read more here.

Keywords: tetra substituted; symmetric tetra; fully symmetric; substituted dota ... See more keywords
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Synthesis of Tetra-Substituted Trifluoromethyl-3,1-Benzoxazines by Transition-Metal-Catalyzed Decarboxylative Cyclization of N-Benzoyl Benzoxazinones.

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Published in 2021 at "ChemistryOpen"

DOI: 10.1002/open.202100094

Abstract: Invited for this month's cover are the group of Norio Shibata at Nagoya Institute of Technology (Japan). The cover picture is inspired by the diversity in the ocean also in cyberspace. In the present research,… read more here.

Keywords: tetra substituted; transition metal; synthesis tetra; benzoxazines transition ... See more keywords
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Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells

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Published in 2019 at "Investigational New Drugs"

DOI: 10.1007/s10637-019-00813-4

Abstract: Cutaneous melanoma, the most aggressive form of skin cancer, is characterized by activating BRAF mutations. Despite the initial success of selective BRAF inhibitors, only few patients exhibited complete responses, whereas many showed disease progression. Melanoma… read more here.

Keywords: tetra substituted; pyrrole derivatives; substituted pyrrole; p53 ... See more keywords
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Aggregation-induced emission and reversible mechanofluorochromic characteristics of tetra-substituted tetrahydropyrimidine derivatives

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Published in 2019 at "Dyes and Pigments"

DOI: 10.1016/j.dyepig.2019.03.004

Abstract: Abstract Organic compounds possessing aggregation-induced emission (AIE) and mechanofluorochromic characteristics are promising in chemo/biosensors and data storage. Here, seven tetra-substituted tetrahydropyrimidine derivatives (TTHPs), products of efficient four-component reactions (4CR), were designed and synthesized for investigation… read more here.

Keywords: emission; mechanofluorochromic characteristics; aggregation induced; tetra substituted ... See more keywords
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Synthesis of tetra-substituted phthalocyanines bearing 2-(ethyl(m-tolyl)amino)ethanol: Computational and photophysicochemical studies

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Published in 2019 at "Journal of Photochemistry and Photobiology A: Chemistry"

DOI: 10.1016/j.jphotochem.2018.12.038

Abstract: Abstract This work presents the synthesis of 4-(2-(ethyl(m-tolyl) amino) ethoxy) phthalonitrile (1) as ligand and its peripherally tetrasubstituted metal-free (2) and metallophthalocyanines (3–5) derivatives. Synthesized compounds were characterized by standart spectroscopy methods. The molecular structure… read more here.

Keywords: synthesis tetra; tetra substituted; tolyl amino; ethyl tolyl ... See more keywords
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DNA/BSA binding studies of peripherally tetra substituted neutral azophenoxy zinc phthalocyanine

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Published in 2020 at "Polyhedron"

DOI: 10.1016/j.poly.2019.114208

Abstract: Abstract A tetra substituted neutral zinc phthalocyanine (ZnPc-4) bearing 4-phenylazophenoxy group at the periphery had been prepared from zinc acetate dihydrate Zn(CH3COO)2·2H2O and 4-(phenylazophenoxy)phthalonitrile. The interaction of neutral metallophthalocyanine, ZnPc-4 with Calf Thymus (CT) DNA… read more here.

Keywords: tetra substituted; dna; substituted neutral; bsa binding ... See more keywords
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Investigation of photophysicochemical properties of non-peripherally tetra-substituted metal-free, Mg(II), Zn(II) and In(III)CI phthalocyanines

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Published in 2020 at "Polyhedron"

DOI: 10.1016/j.poly.2020.114727

Abstract: Abstract In the present work, the synthesis, characterization, photophysicochemical and aggregation properties of non-peripherally tetra-substituted metal-free (H2Pc), Mg(II) (MgPc), Zn(II) (ZnPc), and In(III)CI (InCIPc) phthalocyanines containing tetra (2,3-dihydro-1,4-benzodioxin-2-ylmethoxy) moieties were reported. The spectroscopic techniques were… read more here.

Keywords: tetra substituted; non peripherally; substituted metal; properties non ... See more keywords
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Syntheses of Tetrahydropyran Type 8,7'-Neolignans Using a Ring-Expansion Reaction and Tetrahydrofuran Type 8,7'-Neolignans to Discover a Novel Phytotoxic Neolignan.

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Published in 2023 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.3c01998

Abstract: One novel tri-substituted tetrahydropyran type 8,7'-neolignan and its enantiomer with higher enantiomeric excess were synthesized from all cis-tetra-substituted tetrahydrofuran with an iodomethyl group by a hydride or H2 ring-expansion reaction. The normal hydride reductions of… read more here.

Keywords: type neolignans; tetra substituted; type; expansion reaction ... See more keywords
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Zn(ii) phthalocyanines tetra substituted by aryl and alkyl azides: design, synthesis and optical detection of H2S

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Published in 2020 at "New Journal of Chemistry"

DOI: 10.1039/d0nj00383b

Abstract: Two novel Zn(II)-phthalocyanines having: (i) aryl azide (3) and (ii) alkyl azide (7) functional groups at the peripheral positions have been designed/synthesized for hydrogen sulfide (H2S) sensing purposes, and their photocharacteristic properties were investigated in… read more here.

Keywords: tetra substituted; detection; aryl alkyl; phthalocyanines tetra ... See more keywords
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Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies.

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Published in 2021 at "Dalton transactions"

DOI: 10.1039/d1dt02023d

Abstract: In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted metallophthalocyanines [ZnPc (2), CuPc (3), and CoPc (4)] were synthesized by using 1. The structures of the obtained… read more here.

Keywords: tetra substituted; cell lines; anticancer activity; molecular docking ... See more keywords
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Syntheses, structural characterization, DNA-cleavage and antioxidant features of the new tetra-substituted organo-soluble non-peripherally CoII, CuII, ZnII and MgII phthalocyanines

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Published in 2019 at "Journal of Coordination Chemistry"

DOI: 10.1080/00958972.2019.1648795

Abstract: Abstract This paper encompasses the synthesis, structural characterization, and evaluation of supercoiled pBR322 plasmid DNA-cleavage and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging properties of newly synthesized tetra-substituted CoII (5), CuII (6), ZnII (7) and MgII (8) phthalocyanines… read more here.

Keywords: tetra substituted; structural characterization; characterization; coii cuii ... See more keywords