The selective 5-HT1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat
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DOI: 10.1097/fbp.0000000000000681
Abstract: Tetrabenazine, a preferential inhibitor of the vesicular monoamine transporter type 2, depletes the brain monoamines dopamine, serotonin and norepinephrine. Tetrabenazine and deutetrabenazine (Austedo ®) are used to treat chorea associated with Huntington’s disease. However, both… read more here.
Keywords: ht1a; agonist; nlx 112; induced catalepsy ... See more keywords