Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo.
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DOI: 10.1016/j.ijpharm.2017.09.039
Abstract: In this study, we prepared tetraiodothyroacetic acid (tetrac) conjugated PEG-PLGA polymersomes for the targeted delivery of camptothecin to colon adenocarcinoma. Tetrac, which binds to integrin αvβ3 with high affinity and specificity, was covalently conjugated to… read more here.
Keywords: microscopy; camptothecin; integrin targeted; tetrac conjugated ... See more keywords