Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton
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DOI: 10.1002/cmdc.202000567
Abstract: TGR5, a G‐protein‐coupled receptor (GPCR), plays an important role in several physiological functions. TGR5 activation through bile acids induces an increase in energy expenditure. Therefore, synthetic TGR5 ligands could be useful for the treatment of… read more here.
Keywords: development selective; selective tgr5; skeleton; tetrahydro tetramethylnaphthalene ... See more keywords