Synthesis, in vitro evaluation and molecular docking of new pyrazole derivatives bearing 1,5,10,10a-tetrahydrobenzo[g]quinoline-3-carbonitrile moiety as potent antibacterial agents
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DOI: 10.1007/s13738-020-02086-8
Abstract: In the current study, a new series of pyrazole derivatives 4a – d , 5a – d and 6a – d possessing 1,5,10,10a-tetrahydrobenzo[ g ]quinoline-3-carbonitrile moiety were synthesized by treating chalcones ( 3a – d… read more here.
Keywords: pyrazole derivatives; moiety; quinoline carbonitrile; 10a tetrahydrobenzo ... See more keywords
Anti-proliferative and apoptotic effect of tetrahydrobenzo[h]quinoline on MCF-7 human breast cancer cell
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DOI: 10.34172/ps.2021.58
Abstract: Background: Quinoline and its derivatives display various biological activities based on versatility in designing a new drug class for medicinal applications. Hence, synthesizing innovative and varied derivatives of quinoline has gained considerable attention among chemists… read more here.
Keywords: anti proliferative; effect; quinoline; expression ... See more keywords