The effects of delta-9-tetrahydrocannabinol (THC) on inflammation: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2020.104111
Abstract: THC is the main psychoactive compound found in marijuana. A number of studies over the past few decades, both in vitro and in vivo, have demonstrated that THC down-regulates the inflammatory process through various mechanisms.… read more here.
Keywords: delta tetrahydrocannabinol; inflammation; tetrahydrocannabinol thc; review ... See more keywords
MicroNIR/Chemometrics: A new analytical platform for fast and accurate detection of Δ9-Tetrahydrocannabinol (THC) in oral fluids.
Sign Up to like & getrecommendations! Published in 2019 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2019.107578
Abstract: BACKGROUND Δ9-Tetrahydrocannabinol (THC) is already considered one of the most addictive substances since an increasing number of consumers/abusers of THC and THC based products are observed worldwide. In this work, the capabilities of a novel… read more here.
Keywords: micronir chemometrics; tetrahydrocannabinol thc; oral fluids; thc oral ... See more keywords
Palmitic acid ester of tetrahydrocannabinol (THC) and palmitic acid diester of 11-hydroxy-THC - Unsuccessful search for additional THC metabolites in human body fluids and tissues.
Sign Up to like & getrecommendations! Published in 2019 at "Forensic science international"
DOI: 10.1016/j.forsciint.2018.11.005
Abstract: Fatty acid conjugates of hydroxy-metabolites of tetrahydrocannabinol (THC) or cannabinol have already been reported as metabolites in rats. In the herein presented investigation, palmitic acid esters of THC and its primary metabolite 11-hydroxy-delta9-tetrahydrocannabinol (11-OH-THC) were… read more here.
Keywords: thc palmitic; palmitic acid; tetrahydrocannabinol thc; thc ... See more keywords
Cannabidiol (CBD) but not tetrahydrocannabinol (THC) dysregulate in vitro decidualization of human endometrial stromal cells by disruption of estrogen signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2020.01.003
Abstract: Decidualization, which comprises proliferation and differentiation of endometrial stromal cells (ESCs), is essential for the establishment of a receptive endometrium and pregnancy to occur. A deregulation of decidualization has been associated with miscarriage, infertility and… read more here.
Keywords: cbd; stromal cells; tetrahydrocannabinol thc; endometrial stromal ... See more keywords
Identification of ∆9-tetrahydrocannabinol (THC) impairment using functional brain imaging
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-021-01259-0
Abstract: The primary cannabinoid in cannabis, Δ9-tetrahydrocannabinol (THC), causes intoxication and impaired function, with implications for traffic, workplace, and other situational safety risks. There are currently no evidence-based methods to detect cannabis-impaired driving, and current field… read more here.
Keywords: thc impairment; identification tetrahydrocannabinol; thc; impairment ... See more keywords
CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ9-Tetrahydrocannabinol (Δ9-THC)-Induced Aversive Effects in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12399-z
Abstract: Cannabis can be rewarding or aversive. Cannabis reward is believed to be mediated by activation of cannabinoid CB1 receptors (CB1Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral tegmental area (VTA). However, little… read more here.
Keywords: vglut2 expressing; tetrahydrocannabinol thc; glutamatergic neurons; aversive effects ... See more keywords
Review of delta‐8‐tetrahydrocannabinol (Δ8‐THC): Comparative pharmacology with Δ9‐THC
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15865
Abstract: The use of the intoxicating cannabinoid delta‐8‐tetrahydrocannabinol (Δ8‐THC) has grown rapidly over the last several years. There have been dozens of Δ8‐THC studies dating back over many decades, yet no review articles have comprehensively covered… read more here.
Keywords: pharmacology; delta tetrahydrocannabinol; tetrahydrocannabinol thc; thc ... See more keywords
Acute effects of oral delta-9-tetrahydrocannabinol (THC) on autonomic cardiac activity and their relation to subjective and anxiogenic effects.
Sign Up to like & getrecommendations! Published in 2021 at "Psychophysiology"
DOI: 10.1111/psyp.13955
Abstract: Cannabis is the most commonly used psychotropic drug in the United States, after alcohol. Despite its apparent sedative and calming effects, cannabis and its main psychoactive constituent, ∆9 -tetrahydrocannabinol (THC) can produce serious adverse effects… read more here.
Keywords: drug; relation subjective; tetrahydrocannabinol thc; thc autonomic ... See more keywords
Acute effect of delta-9-tetrahydrocannabinol (THC) on neuromuscular transmission and locomotive behaviours in larval zebrafish.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurophysiology"
DOI: 10.1152/jn.00438.2022
Abstract: Given the increasing trend of cannabis use for recreational and therapeutic purposes, a comprehensive examination of cannabis effects is warranted. The principal psychoactive constituent of cannabis, delta-9-tetrahydrocannabinol (THC), is a potent disrupter of neurodevelopment. Nevertheless,… read more here.
Keywords: locomotive behaviours; delta tetrahydrocannabinol; neuromuscular transmission; tetrahydrocannabinol thc ... See more keywords
Current Cannabidiol Safety: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug safety"
DOI: 10.2174/1574886317666220902100511
Abstract: Background- Marijuana, also known as cannabis, is the second most widely used illegal psychoactive substance smoked worldwide after tobacco, mainly due to the psychoactive effects induced by D-9-tetrahydrocannabinol (9-THC). Cannabidiol (CBD) is extracted from cannabis… read more here.
Keywords: safety; cannabis; review; cannabidiol ... See more keywords
Acute human exposure assessment to tetrahydrocannabinol (Δ9‐THC)
Sign Up to like & getrecommendations! Published in 2020 at "EFSA Journal"
DOI: 10.2903/j.efsa.2020.5953
Abstract: Abstract Delta‐9‐tetrahydrocannabinol (Δ9‐THC) is a naturally occurring psychoactive compound derived from the hemp plant Cannabis sativa. In 2015, EFSA established an acute reference dose (ARfD) of 1 μg/kg body weight (bw) for Δ9‐THC and assessed… read more here.
Keywords: hemp; tetrahydrocannabinol thc; exposure; human exposure ... See more keywords