Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
Sign Up to like & getrecommendations! Published in 2017 at "Natural Products and Bioprospecting"
DOI: 10.1007/s13659-017-0143-9
Abstract: Tetrahydrocurcumin (THC) is a major metabolite of curcumin and plays an important role in curcumin-induced biological effects. THC is a promising preventive and chemotherapeutic agent for cancer. A series of new pyrazole derivatives of THC… read more here.
Keywords: tetrahydrocurcumin; cancer; synthesis cytotoxic; cell ... See more keywords
Production of Tetrahydrocurcumin From Curcumin by Cultured Plant Cells and Inhibitory Effects of Curcuminoids on NF-κB Activity
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x19878920
Abstract: Biotransformation of curcumin was investigated using cultured plant cells of Morus sp. Cultured Morus cells converted curcumin into dihydrocurcumin and tetrahydrocurcumin. The activity of nuclear factor-κB was inhibited by curcumin and tetrahydrocurcumin. read more here.
Keywords: curcumin; tetrahydrocurcumin; activity; cultured plant ... See more keywords