Synthesis of Tetrahydrofurans and Pyrrolidines by Copper-Catalyzed Oxy/Aminoarylation of Alkenes.
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DOI: 10.1021/acs.orglett.3c01265
Abstract: An efficient copper-catalyzed inter/intramolecular oxy/aminoarylation of γ-hydroxy/aminoalkenes with diaryliodonium triflates is reported. Simple activation of these arylating agents with copper(II) triflate in dichloromethane triggers a smooth activation of the alkene, which is simultaneously trapped by… read more here.
Keywords: tetrahydrofurans pyrrolidines; copper catalyzed; oxy aminoarylation; synthesis tetrahydrofurans ... See more keywords