C(sp3)-H Alkenylation of Tetrahydroisoquinolines via Merging Electrochemistry and Organocatalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04136
Abstract: C(sp3)-H alkenylation of tetrahydroisoquinoline by merging Shono oxidation and the Morita-Baylis-Hillman reaction is developed, employing 4-dimethylaminopyridine as an organocatalyst and TEMPO/NaBr as an electrocatalyst. The reaction proceeds via the interception of an iminium cation intermediate,… read more here.
Keywords: sp3 alkenylation; reaction; electrochemistry; tetrahydroisoquinolines via ... See more keywords