Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands.
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DOI: 10.1021/acs.jmedchem.8b00359
Abstract: A new family of melatonin receptor ligands, characterized by a tetrahydroquinoline (THQ) scaffold carrying an amide chain in position 3, was devised as conformationally constrained analogs of flexible N-anilinoethylamides previously developed. Molecular superposition models allowed… read more here.
Keywords: tetrahydroquinoline ring; ring versatile; receptor ligands; receptor ... See more keywords