2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside promotes the effects of dental pulp stem cells on rebuilding periodontal tissues in experimental periodontal defects.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of periodontology"
DOI: 10.1002/jper.19-0563
Abstract: BACKGROUND This study aimed to investigate the regenerative effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG)-treated human dental pulp stem cells (DPSC) on the healing of experimental periodontal defects in rats. MATERIALS AND METHODS The maxillary first molars of… read more here.
Keywords: dpsc thsg; tetrahydroxystilbene glucoside; periodontal defects; dental pulp ... See more keywords
Determination and correlation of the solubility and thermodynamic parameters of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside in pure organic solvents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.02.046
Abstract: Abstract The solubility of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) was measured in nine organic solvents (methanol, ethanol, n-propanol, i-propanol, ethyl acetate, acetone, acetonitrile, N,N-dimethylformamide (DMF), and tetrahydrofuran (THF)) in the temperature range 278.15 to 318.15 K at atmosphere pressure… read more here.
Keywords: organic solvents; temperature; correlation; solubility ... See more keywords
Tetrahydroxystilbene glucoside-induced relaxation of the superior mesenteric artery via both endothelium-dependent and endothelium-independent mechanisms.
Sign Up to like & getrecommendations! Published in 2019 at "Microvascular research"
DOI: 10.1016/j.mvr.2018.10.007
Abstract: Tetrahydroxystilbene glucoside (TSG) is the main water-soluble component in Polygonum multiflorum Thunb, and it has many cardioprotective effects. Although TSG is able to relax blood vessels, its relaxation of rat superior mesenteric arteries and the… read more here.
Keywords: superior mesenteric; endothelium; relaxation; tsg ... See more keywords
Chemopreventive Potential of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside on the Formation of Aberrant Crypt Foci in Azoxymethane-Induced Colorectal Cancer in Rats
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/3634915
Abstract: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG) has been shown to have antioxidative and anti-inflammatory effects. Oxidative and inflammatory reactions are related to the development of colorectal carcinoma (CRC). In the present study, we characterized the preventive activities of THSG… read more here.
Keywords: aberrant crypt; tetrahydroxystilbene glucoside; crypt foci;
Tetrahydroxystilbene Glucoside Produces Neuroprotection against 6-OHDA-Induced Dopamine Neurotoxicity
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/7927568
Abstract: Parkinson's disease (PD) was one of the most common neurodegenerative diseases with a slow and progressive loss of dopamine (DA) neurons in the midbrain substantia nigra (SN). Neuroinflammation was identified to be an important contributor… read more here.
Keywords: neurotoxicity; neuroprotection; ohda induced; tetrahydroxystilbene glucoside ... See more keywords
Cognitive enhancing and antioxidant effects of tetrahydroxystilbene glucoside in Aβ1-42-induced neurodegeneration in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of integrative neuroscience"
DOI: 10.31083/jin-170059
Abstract: Polyhydroxy stilbenes have been reported to possess various biological activities and have potential for treatment of Alzheimer's disease. Tetrahydroxystilbene glucoside is one of the major polyhydroxy stilbenes, which provides the underlying therapeutic activities for neuroprotective… read more here.
Keywords: erythroid; alzheimer disease; kelch like; tetrahydroxystilbene glucoside ... See more keywords
2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside improves female ovarian aging
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.862045
Abstract: Reduced fertility associated with normal aging may reflect the over-maturity of oocytes. It is increasingly important to reduce aging-induced infertility since recent trends show people marrying at later ages. 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG), a polyphenol extracted from… read more here.
Keywords: thsg; expression; group; aged mice ... See more keywords
A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.791214
Abstract: Polygonum multiflorum Thunb. (He-shou-wu in Chinese), a Chinese botanical drug with a long history, is widely used to treat a variety of chronic diseases in clinic, and has been given the reputation of “rejuvenating and… read more here.
Keywords: tsg; pharmacology; review; toxicity pharmacokinetics ... See more keywords
2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.997100
Abstract: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside (THSG) is the main active ingredient extracted from Polygonum multiflorum Thunb. (PMT), which has been reported to possess extensive pharmacological properties. Nevertheless, the exact role of THSG in pulmonary fibrosis has not been demonstrated… read more here.
Keywords: thsg; expression; pulmonary fibrosis; tgf ... See more keywords
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2022.5127
Abstract: Gentamicin is an important aminoglycoside antibiotic used in the treatment of gram‑negative bacterial infections, but nephrotoxicity and ototoxicity reduce its utility. The autophagy pathway is involved in damage of auditory hair cells. With the aim… read more here.
Keywords: ampk mtor; tetrahydroxystilbene glucoside; gentamicin induced; ototoxicity ... See more keywords