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Published in 2020 at "Journal of periodontology"
DOI: 10.1002/jper.19-0563
Abstract: BACKGROUND This study aimed to investigate the regenerative effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG)-treated human dental pulp stem cells (DPSC) on the healing of experimental periodontal defects in rats. MATERIALS AND METHODS The maxillary first molars of…
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Keywords:
dpsc thsg;
tetrahydroxystilbene glucoside;
periodontal defects;
dental pulp ... See more keywords
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Published in 2018 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.02.046
Abstract: Abstract The solubility of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) was measured in nine organic solvents (methanol, ethanol, n-propanol, i-propanol, ethyl acetate, acetone, acetonitrile, N,N-dimethylformamide (DMF), and tetrahydrofuran (THF)) in the temperature range 278.15 to 318.15 K at atmosphere pressure…
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Keywords:
organic solvents;
temperature;
correlation;
solubility ... See more keywords
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Published in 2019 at "Microvascular research"
DOI: 10.1016/j.mvr.2018.10.007
Abstract: Tetrahydroxystilbene glucoside (TSG) is the main water-soluble component in Polygonum multiflorum Thunb, and it has many cardioprotective effects. Although TSG is able to relax blood vessels, its relaxation of rat superior mesenteric arteries and the…
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Keywords:
superior mesenteric;
endothelium;
relaxation;
tsg ... See more keywords
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Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/3634915
Abstract: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG) has been shown to have antioxidative and anti-inflammatory effects. Oxidative and inflammatory reactions are related to the development of colorectal carcinoma (CRC). In the present study, we characterized the preventive activities of THSG…
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Keywords:
aberrant crypt;
tetrahydroxystilbene glucoside;
crypt foci;
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Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/7927568
Abstract: Parkinson's disease (PD) was one of the most common neurodegenerative diseases with a slow and progressive loss of dopamine (DA) neurons in the midbrain substantia nigra (SN). Neuroinflammation was identified to be an important contributor…
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Keywords:
neurotoxicity;
neuroprotection;
ohda induced;
tetrahydroxystilbene glucoside ... See more keywords
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Published in 2018 at "Journal of integrative neuroscience"
DOI: 10.31083/jin-170059
Abstract: Polyhydroxy stilbenes have been reported to possess various biological activities and have potential for treatment of Alzheimer's disease. Tetrahydroxystilbene glucoside is one of the major polyhydroxy stilbenes, which provides the underlying therapeutic activities for neuroprotective…
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Keywords:
erythroid;
alzheimer disease;
kelch like;
tetrahydroxystilbene glucoside ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.862045
Abstract: Reduced fertility associated with normal aging may reflect the over-maturity of oocytes. It is increasingly important to reduce aging-induced infertility since recent trends show people marrying at later ages. 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG), a polyphenol extracted from…
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Keywords:
thsg;
expression;
group;
aged mice ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.791214
Abstract: Polygonum multiflorum Thunb. (He-shou-wu in Chinese), a Chinese botanical drug with a long history, is widely used to treat a variety of chronic diseases in clinic, and has been given the reputation of “rejuvenating and…
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Keywords:
tsg;
pharmacology;
review;
toxicity pharmacokinetics ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.997100
Abstract: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside (THSG) is the main active ingredient extracted from Polygonum multiflorum Thunb. (PMT), which has been reported to possess extensive pharmacological properties. Nevertheless, the exact role of THSG in pulmonary fibrosis has not been demonstrated…
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Keywords:
thsg;
expression;
pulmonary fibrosis;
tgf ... See more keywords
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Published in 2022 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2022.5127
Abstract: Gentamicin is an important aminoglycoside antibiotic used in the treatment of gram‑negative bacterial infections, but nephrotoxicity and ototoxicity reduce its utility. The autophagy pathway is involved in damage of auditory hair cells. With the aim…
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Keywords:
ampk mtor;
tetrahydroxystilbene glucoside;
gentamicin induced;
ototoxicity ... See more keywords