Functional analysis of metallothionein MTT5 from Tetrahymena thermophila
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26482
Abstract: Metallothioneins (MTs) constitute a superfamily of cysteine‐rich proteins that bind heavy‐metal ions by metal‐thiolate clusters. Five MT genes from Tetrahymena thermophila was subdivided into 7a (MTT1, MTT3, and MTT5) and 7b (MTT2 and MTT4) subfamilies.… read more here.
Keywords: mtt5; cd2; tetrahymena thermophila; coli pgex ... See more keywords
Identification of the zinc, copper and cadmium metalloproteome of the protozoon Tetrahymena thermophila by systematic bioinformatics
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Microbiology"
DOI: 10.1007/s00203-017-1385-y
Abstract: Tetrahymena thermophila (T. thermophila) is a ciliated protozoon that can detect freshwater pollution by heavy metals (“whole-cell biosensor”). This work employed a systematic bioinformatics approach to predict and analyze the metalloproteome of T. thermophila for… read more here.
Keywords: protozoon; systematic bioinformatics; metalloproteome; tetrahymena thermophila ... See more keywords
The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2019.06.052
Abstract: Mediator is a large protein complex required for basal and regulated expression of most RNA polymerase II (RNAP II)-transcribed genes, in part due to its interaction with and phosphorylation of the conserved C-terminal domain (CTD)… read more here.
Keywords: mediator; tetrahymena thermophila; mediator complex; regulation ... See more keywords
Molecular mechanisms underlying the calcium-mediated uptake of hematite nanoparticles by the ciliate Tetrahymena thermophila.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117749
Abstract: In aquatic ecosystems, the calcium (Ca) concentration varies greatly. It is well known that Ca affects the aggregation of nanoparticles (NPs) and thus their bioaccumulation. Nevertheless, Ca also plays critical roles in various biological processes,… read more here.
Keywords: underlying calcium; tetrahymena thermophila; ciliate tetrahymena; mechanisms underlying ... See more keywords
Characterization and use of Tetrahymena thermophila artificial chromosome 2 (TtAC2) constructed by biomimetic of macronuclear rDNA minichromosome.
Sign Up to like & getrecommendations! Published in 2021 at "Microbiological research"
DOI: 10.1016/j.micres.2021.126764
Abstract: Efficient expression vectors for unicellular ciliate eukaryotic Tetrahymena thermophila are still needed in recombinant biology and biotechnology applications. Previously, the construction of the T. thermophila Macronuclear Artificial Chromosome 1 (TtAC1) vector revealed additional needs for… read more here.
Keywords: ttac2; tetrahymena thermophila; rdna; artificial chromosome ... See more keywords
Fusion to Tetrahymena thermophila granule lattice protein 1 confers solubility to sexual stage malaria antigens in Escherichia coli
Sign Up to like & getrecommendations! Published in 2019 at "Protein Expression and Purification"
DOI: 10.1016/j.pep.2018.08.001
Abstract: A transmission-blocking vaccine targeting the sexual stages of Plasmodium species could play a key role in eradicating malaria. Multiple studies have identified the P. falciparum proteins Pfs25 and Pfs48/45 as prime targets for transmission-blocking vaccines.… read more here.
Keywords: protein; lattice protein; tetrahymena thermophila; granule lattice ... See more keywords
Drivers of Mating Type Composition in Tetrahymena thermophila
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa197
Abstract: Abstract Sex offers advantages even in primarily asexual species. Some ciliates appear to utilize such reproductive strategy with many mating types. However, the factors determining the composition of mating types in the unicellular ciliate Tetrahymena… read more here.
Keywords: type composition; mating type; tetrahymena thermophila; mating types ... See more keywords
Gene swamping alters evolution during range expansions in the protist Tetrahymena thermophila
Sign Up to like & getrecommendations! Published in 2020 at "Biology Letters"
DOI: 10.1098/rsbl.2020.0244
Abstract: At species’ range edges, individuals often face novel environmental conditions that may limit range expansion until populations adapt. The potential to adapt depends on genetic variation upon which selection can act. However, populations at species’… read more here.
Keywords: range expansions; tetrahymena thermophila; swamping alters; gene swamping ... See more keywords
Case Study of the Response of N6-Methyladenine DNA Modification to Environmental Stressors in the Unicellular Eukaryote Tetrahymena thermophila
Sign Up to like & getrecommendations! Published in 2021 at "mSphere"
DOI: 10.1128/msphere.01208-20
Abstract: Increasing evidence indicated that 6mA could respond to environmental stressors in multicellular eukaryotes. As 6mA distribution and function differ significantly in multicellular and unicellular organisms, whether and how 6mA in unicellular eukaryotes responds to environmental… read more here.
Keywords: tetrahymena thermophila; response; starvation; environmental stressors ... See more keywords
A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010194
Abstract: In the ciliate Tetrahymena thermophila, lysosome-related organelles called mucocysts accumulate at the cell periphery where they secrete their contents in response to extracellular events, a phenomenon called regulated exocytosis. The molecular bases underlying regulated exocytosis… read more here.
Keywords: mucocyst; exocytosis; regulated exocytosis; tetrahymena thermophila ... See more keywords
Extreme metal adapted, knockout and knockdown strains reveal a coordinated gene expression among different Tetrahymena thermophila metallothionein isoforms
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0189076
Abstract: Metallothioneins (MT) constitute a superfamily of small cytosolic proteins that are able to bind metal cations through numerous cysteine (Cys) residues. Like other organisms the ciliate Tetrahymena thermophila presents several MT isoforms, which have been… read more here.
Keywords: extreme metal; tetrahymena thermophila; knockdown strains; gene ... See more keywords