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Tetramodal Chemical Imaging Delineates the Lipid–Amyloid Peptide Interplay at Single Plaques in Transgenic Alzheimer’s Disease Models

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Published in 2023 at "Analytical Chemistry"

DOI: 10.1021/acs.analchem.2c05302

Abstract: Beta-amyloid (Aβ) plaque pathology is one of the most prominent histopathological feature of Alzheimer’s disease (AD). The exact pathogenic mechanisms linking Aβ to AD pathogenesis remain however not fully understood. Recent advances in amyloid-targeting pharmacotherapies… read more here.

Keywords: alzheimer disease; microscopy; plaque; single plaques ... See more keywords