Articles with "tetrapeptide hdac" as a keyword



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Cyclic Tetrapeptide HDAC Inhibitors with Improved Plasmodium falciparum Selectivity and Killing Profile.

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Published in 2021 at "ACS infectious diseases"

DOI: 10.1021/acsinfecdis.1c00341

Abstract: Cyclic tetrapeptide histone deacetylase inhibitors represent a promising class of antiplasmodial agents that epigenetically disrupt a wide range of cellular processes in Plasmodium falciparum. Unfortunately, certain limitations, including reversible killing effects and host cell toxicity,… read more here.

Keywords: cyclic tetrapeptide; tetrapeptide hdac; hdac inhibitors; plasmodium falciparum ... See more keywords