Loss of tetraspanin‐7 expression reduces pancreatic β‐cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism
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DOI: 10.1111/dme.14984
Abstract: Tetraspanin‐7 (Tspan7) is an islet autoantigen involved in autoimmune type 1 diabetes and known to regulate β‐cell L‐type Ca2+ channel activity. However, the role of Tspan7 in pancreatic β‐cell function is not yet fully understood. read more here.
Keywords: cell; tetraspanin expression; pancreatic cell; loss tetraspanin ... See more keywords
Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers
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DOI: 10.1186/s12951-021-00987-1
Abstract: Background Tetraspanin expression of extracellular vesicles (EVs) is often used as a surrogate for their detection and classification, a practice that typically assumes their consistent expression across EV sources. Results Here we demonstrate that there… read more here.
Keywords: extracellular vesicles; detection; sensitivity; expression ... See more keywords