The use of enaminones and enamines as effective synthons for MSA-catalyzed regioselective synthesis of 1,3,4-tri- and 1,3,4,5-tetrasubstituted pyrazoles
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DOI: 10.1039/c9nj03701b
Abstract: In the present work, an efficient regioselective synthesis of 1,3,4-tri- and 1,3,4,5-tetrasubstituted pyrazoles via a methanesulfonic acid (MSA)-catalyzed reaction of hydrazones with enaminones or enamines is reported. read more here.
Keywords: tetrasubstituted pyrazoles; msa catalyzed; synthesis tri; enaminones enamines ... See more keywords
Synthesis of tetrasubstituted pyrazoles containing pyridinyl substituents
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DOI: 10.3762/bjoc.13.90
Abstract: A synthesis of tetrasubstituted pyrazoles containing two, three or four pyridinyl substituents is described. Hence, the reaction of 1,3-dipyridinyl-1,3-propanediones with 2-hydrazinopyridine or phenylhydrazine, respectively, affords the corresponding 1,3,5-trisubstituted pyrazoles. Iodination at the 4-position of the… read more here.
Keywords: tetrasubstituted pyrazoles; pyrazoles containing; pyridinyl substituents; synthesis tetrasubstituted ... See more keywords