Tetrodotoxin levels of three pufferfish species (Lagocephalus sp.) caught in the North-Eastern Mediterranean sea.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.12.010
Abstract: Tetrodotoxin (TTX) levels in Lagocephalus sceleratus (Silverstripe blaasop), Lagocephalus spadiceus (Half-smooth golden pufferfish) and Lagocephalus suezensis (Suez puffer) caught in Mersin Bay in the Northeastern Mediterranean Sea were analysed using Q-TOF LC/MS. Pufferfish were caught… read more here.
Keywords: tetrodotoxin; eastern mediterranean; mediterranean sea; north eastern ... See more keywords
New tetrodotoxin analogs in Brazilian pufferfishes tissues and microbiome.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.125211
Abstract: While tetrodotoxin (TTX) is commonly found in pufferfish tissues, it is unclear if bacterial symbionts isolated from pufferfish tissues can produce TTX. In this investigation, UPLC qTOF-MS/MS analysis of tissue extracts obtained from Sphoeroides spengleri… read more here.
Keywords: tetrodotoxin; brazilian pufferfishes; tetrodotoxin analogs; analogs brazilian ... See more keywords
Role of maternal tetrodotoxin in survival of larval pufferfish
Sign Up to like & getrecommendations! Published in 2018 at "Toxicon"
DOI: 10.1016/j.toxicon.2018.04.014
Abstract: ABSTRACT It is known that tetrodotoxin (TTX), also known as pufferfish toxin, is an extremely potent neurotoxin and had been detected in various taxa. However, the exact function of the toxin in TTX‐bearing organisms has… read more here.
Keywords: non toxic; tetrodotoxin; larval pufferfish; toxic larvae ... See more keywords
Hybrid Antibody-Aptamer Assay for Detection of Tetrodotoxin in Pufferfish.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03671
Abstract: The marine toxin tetrodotoxin (TTX) poses a great risk to public health safety due to its severe paralytic effects after ingestion. Seafood poisoning caused by the consumption of contaminated marine species like pufferfish due to… read more here.
Keywords: detection; tetrodotoxin; aptamer assay; antibody aptamer ... See more keywords
Tetrodotoxin and Its Analogues in Food: Recent Updates on Sample Preparation and Analytical Methods Since 2012.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04106
Abstract: Tetrodotoxin (TTX), found in various organisms including pufferfish, is an extremely potent marine toxin responsible for numerous food poisoning accidents. Due to its serious toxicity and public health threat, detecting TTX and its analogues in… read more here.
Keywords: analytical methods; food; sample preparation; tetrodotoxin ... See more keywords
Quantitation of Tetrodotoxin and Its Analogues with a Combination of Liquid Chromatography-Tandem Mass Spectrometry and Quantitative 1H-NMR Spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b06380
Abstract: Tetrodotoxin and its analogues are the causative toxins of pufferfish poisoning. Tetrodotoxin was recently detected in bivalve mollusks collected in New Zealand and Europe, highlighting the need to include tetrodotoxin in monitoring programs for bivalves… read more here.
Keywords: chromatography tandem; tetrodotoxin; quantitation; tetrodotoxin analogues ... See more keywords
Photoelectric Bacteria Enhance the In Situ Production of Tetrodotoxin for Antitumor Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.1c00408
Abstract: Engineered bacteria are promising bioagents to synthesize antitumor drugs at tumor sites with the advantages of avoiding drug leakage and degradation during delivery. Here, we report an optically controlled material-assisted microbial system by biosynthesizing gold… read more here.
Keywords: antitumor therapy; production; tetrodotoxin; photoelectric bacteria ... See more keywords
An Oxidative Dearomatization Approach to Tetrodotoxin via a Masked ortho-Benzoquinone.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03998
Abstract: Progress toward a stereoselective synthesis of tetrodotoxin (TTX) is presented. Oxidative dearomatization of a tetrasubstituted guaiacol arene yielded a masked ortho-benzoquinone that intercepted an acyl nitroso species generated in situ by the copper-catalyzed aerobic oxidation… read more here.
Keywords: masked ortho; oxidative dearomatization; ortho benzoquinone; tetrodotoxin ... See more keywords
Interlaboratory Evaluation of Multiple LC–MS/MS Methods and a Commercial ELISA Method for Determination of Tetrodotoxin in Oysters and Mussels
Sign Up to like & getrecommendations! Published in 2023 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsad006
Abstract: Abstract Background Given the recent detection of tetrodotoxin (TTX) in bivalve molluscs but the absence of a full collaborative validation study for TTX determination in a large number of shellfish samples, interlaboratory assessment of method… read more here.
Keywords: methods commercial; tetrodotoxin; ttx; commercial elisa ... See more keywords
A concise synthesis of tetrodotoxin
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abn0571
Abstract: Tetrodotoxin (TTX) is a neurotoxic natural product that is an indispensable probe in neuroscience, a biosynthetic and ecological enigma, and a celebrated target of synthetic chemistry. Here, we present a stereoselective synthesis of TTX that… read more here.
Keywords: dipolar cycloaddition; tetrodotoxin; synthesis; ttx ... See more keywords
Sensitive and rapid detection of tetrodotoxin based on gold nanoflower-and latex microsphere-labeled monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1196043
Abstract: Tetrodotoxin (TTX) could result in serious diseases due to its extremely high neurotoxicity. Thus, it is of great importance to measure TTX for food safety. In this study, an anti-TTX monoclonal antibody with good specificity… read more here.
Keywords: tetrodotoxin; rapid detection; latex microsphere; detection ... See more keywords