Articles with "tf27" as a keyword



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Artesunate derivative TF27 inhibits replication and pathogenesis of an oncogenic avian alphaherpesvirus.

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Published in 2019 at "Antiviral research"

DOI: 10.1016/j.antiviral.2019.104606

Abstract: Nucleoside analogues have been the cornerstone of clinical treatment of herpesvirus infections since the 1970s. However, severe side effects and emergence of drug resistant viruses raise the need for alternative treatment options. We recently investigated… read more here.

Keywords: tf27; artesunate derivative; derivative tf27; replication ... See more keywords
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The Trimeric Artesunate Analog TF27, a Broadly Acting Anti-Infective Model Drug, Exerts Pronounced Anti-SARS-CoV-2 Activity Spanning Variants and Host Cell Types

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15010115

Abstract: Starting in 2019, the spread of respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated pandemic of the corona virus disease (COVID-19) has led to enormous efforts in the development of medical countermeasures. Although innovative vaccines… read more here.

Keywords: broadly acting; activity; tf27; cov activity ... See more keywords