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   Articles with "tfap2c" as a keyword



Generation of Tfap2c‐T2A‐tdTomato knock‐in reporter rats via adeno‐associated virus‐mediated efficient gene targeting

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recommendations! Published in 2022 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.23562

Abstract: Gene editing in mammalian zygotes enables us to generate genetically modified animals rapidly and efficiently. In this study, we compare multiple gene targeting strategies in rat zygotes by generating a novel knock‐in reporter rat line… read more here.

Keywords: reporter; tfap2c t2a; gene targeting; tfap2c ... See more keywords

TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway

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recommendations! Published in 2024 at "Biology Direct"

DOI: 10.1186/s13062-024-00584-w

Abstract: Six-transmembrane epithelial antigen of prostate 3 (STEAP3) is associated with the progression of several human malignancies. However, its role in lung squamous cell carcinoma (LUSC) remains unclear. We measured STEAP3 expression in LUSC cell lines… read more here.

Keywords: lung squamous; progression; cell; squamous cell ... See more keywords

Does TFAP2C govern conflicting cell-fates in mouse preimplantation embryos?

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recommendations! Published in 2024 at "Reproduction"

DOI: 10.1530/rep-23-0440

Abstract: TFAP2C is a well-established regulator of the trophoblast lineage in mice and humans, but a handful of studies indicate that TFAP2C may play an important role in pluripotency. Here we hypothesize and provide new evidence… read more here.

Keywords: tfap2c govern; cell fates; preimplantation; govern conflicting ... See more keywords

TFAP2C exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells activation through regulating TEAD4 transcription

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recommendations! Published in 2023 at "Allergologia et Immunopathologia"

DOI: 10.15586/aei.v51i3.854

Abstract: Background: Psoriasis is one of the chronic and autoimmune skin diseases. It is important to uncover the mechanisms underlying the psoriasis. Transcription factor activator protein (TFAP-2) gamma, also known as AP2-gamma, is a protein encoded… read more here.

Keywords: th17 th1; transcription; th1 cells; tfap2c ... See more keywords