A TRP Family Based Signature for Prognosis Prediction in Head and Neck Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/8757656
Abstract: Purpose Head and neck squamous cell carcinoma (HNSCC) is a classical type of head and neck cancers, with heterogeneous clinical outcome. This project is set out to create a robust risk signature based on TRP… read more here.
Keywords: prognosis; head neck; signature; tfbs ... See more keywords
Transcription factor binding site clusters identify target genes with similar tissue-wide expression and buffer against mutations
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DOI: 10.12688/f1000research.17363.2
Abstract: Background: The distribution and composition of cis-regulatory modules composed of transcription factor (TF) binding site (TFBS) clusters in promoters substantially determine gene expression patterns and TF targets. TF knockdown experiments have revealed that TF binding… read more here.
Keywords: expression patterns; binding site; tissue wide; expression ... See more keywords
Plant-DTI: Extending the landscape of TF protein and DNA interaction in plants by a machine learning-based approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.970018
Abstract: As a sessile organism, plants hold elaborate transcriptional regulatory systems that allow them to adapt to variable surrounding environments. Current understanding of plant regulatory mechanisms is greatly constrained by limited knowledge of transcription factor (TF)–DNA… read more here.
Keywords: dbd; plant dti; tfbs; machine learning ... See more keywords