A novel RBMX‐TFE3 gene fusion in a highly aggressive pediatric renal perivascular epithelioid cell tumor
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1002/gcc.22801
Abstract: We report an Xp11 translocation perivascular epithelioid cell tumor (PEComa) with a novel RBMX‐TFE3 gene fusion, resulting from a paracentric X chromosome inversion, inv(X)(p11;q26). The neoplasm occurred in an otherwise healthy 12‐year‐old boy who presented… read more here.
Keywords: rbmx tfe3; gene fusion; rbmx; tfe3 gene ... See more keywords
Renal cancer associated with Xp11.2 translocation/TFE3 gene fusion: Clinicopathological analysis of 13 cases.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2022.151908
Abstract: OBJECTIVE To explore the clinicopathological characteristics, immunohistochemical phenotype, diagnosis and differential diagnosis of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion. METHODS The clinical history, pathological morphology, immunohistochemical phenotype and related molecular test results… read more here.
Keywords: tfe3 gene; gene fusion; gene; translocation tfe3 ... See more keywords
Renal Cell Carcinoma Associated With Xp11.2 Translocation/TFE3 Gene-fusion: A Long Response to mammalian target of rapamycin (mTOR) Inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "Urology"
DOI: 10.1016/j.urology.2018.03.032
Abstract: Objective To demonstrate that patients with Xp11.2/TFE3 gene-fusion translocation renal cell carcinoma (RCC), despite having an aggressive course in young adults, could have valid treatment options such as mammalian target of rapamycin (mTOR) inhibitors with… read more here.
Keywords: tfe3 gene; gene fusion; mtor; mtor inhibitors ... See more keywords
YAP1-TFE3 Gene Fusion Variant in Clear Cell Stromal Tumor of Lung: Report of Two Cases in Support of a Distinct Entity.
Sign Up to like & getrecommendations! Published in 2021 at "Histopathology"
DOI: 10.1111/his.14437
Abstract: AIMS Clear cell (hemangioblastoma-like) stromal tumor of the lung is a newly described, rare pulmonary neoplasm. Recurrent YAP1-TFE3 gene fusions have recently been reported in three cases. We describe two additional cases and confirm the… read more here.
Keywords: tumor lung; tfe3 gene; yap1 tfe3; fusion ... See more keywords
Adult renal cell carcinoma associated with TFE3 gene fusions: a case report
Sign Up to like & getrecommendations! Published in 2020 at "International Urology and Nephrology"
DOI: 10.3760/cma.j.issn.1673-4416.2020.01.040
Abstract: 转录因子E3(TFE3)基因融合肾癌是一种罕见的肾细胞癌亚型，好发于儿童和青少年。成人TFE3基因融合肾癌发病率仅占成人肾细胞癌的1%，且具有临床侵袭性，预后较差。本文报道1例成人TFE3基因融合肾癌，采用肾部分切除术治疗，结合文献复习，讨论术后的进一步治疗方案，以供临床参考。 read more here.
Keywords: renal cell; cell carcinoma; carcinoma associated; adult renal ... See more keywords