Articles with "tfg" as a keyword



Mutation Screening of TFG in α‐Synucleinopathy and Amyotrophic Lateral Sclerosis

Sign Up to like & get
recommendations!
Published in 2022 at "Movement Disorders"

DOI: 10.1002/mds.29079

Abstract: Recently, p.R383H in TFG was identified as the disease cause in a family with α‐synucleinopathy and amyotrophic lateral sclerosis (ALS). However, no further replication has been conducted in larger cohorts. read more here.

Keywords: mutation screening; synucleinopathy amyotrophic; lateral sclerosis; tfg ... See more keywords
Photo by nci from unsplash

Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation

Sign Up to like & get
recommendations!
Published in 2018 at "Cell reports"

DOI: 10.1016/j.celrep.2018.07.081

Abstract: SUMMARY Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and is characteristic of several neurological disorders, including hereditary spastic paraplegia (HSP) and amyotrophic lateral sclerosis. Mutations in Trk-fused gene (TFG) have been implicated… read more here.

Keywords: hereditary spastic; axon fasciculation; tfg; spastic paraplegia ... See more keywords

Smoking related outcomes before and after implementation of tobacco-free grounds in residential substance use disorder treatment programs.

Sign Up to like & get
recommendations!
Published in 2019 at "Drug and alcohol dependence"

DOI: 10.1016/j.drugalcdep.2019.01.001

Abstract: BACKGROUND This study examined the impact of a tobacco-free grounds (TFG) policy and the California $2.00/pack tobacco tax increase on tobacco use among individuals in residential substance use disorder (SUD) treatment. METHODS We conducted three… read more here.

Keywords: use; treatment programs; treatment; tfg ... See more keywords

Flash Graphene Morphologies.

Sign Up to like & get
recommendations!
Published in 2020 at "ACS nano"

DOI: 10.1021/acsnano.0c05900

Abstract: Flash Joule heating (FJH) can convert almost any carbon-based precursor into bulk quantities of graphene. This work explores the morphologies and properties of flash graphene (FG) generated from carbon black. It is shown that FG… read more here.

Keywords: carbon; flash graphene; graphene; bulk ... See more keywords

Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity

Sign Up to like & get
recommendations!
Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-13432-x

Abstract: The Trk-fused gene (TFG) is reportedly involved in the process of COPII-mediated vesicle transport and missense mutations in TFG cause several neurodegenerative diseases including hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P). The… read more here.

Keywords: insulin; trk fused; tfg; fused gene ... See more keywords

Tropomyosin-receptor kinase fused gene (TFG) regulates lipid production in human sebocytes

Sign Up to like & get
recommendations!
Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-43209-3

Abstract: The endoplasmic reticulum (ER) is an organelle in which important cellular events such as protein synthesis and lipid production occur. Although many lipid molecules are produced in the ER, the effect of ER-organizing proteins on… read more here.

Keywords: receptor kinase; production; lipid production; tfg ... See more keywords

TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance

Sign Up to like & get
recommendations!
Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2210649119

Abstract: Significance Pathological mutations in TFG have been implicated in a variety of neurodegenerative diseases, including early-onset forms of hereditary spastic paraplegia (HSP). In this work, we demonstrate that the TFG p.R106C mutation, which has been… read more here.

Keywords: secretory endosomal; maintenance; regulates secretory; tfg ... See more keywords

Green synthesis of silver nanoparticles reduced with Trigonella foenum-graecum and their effect on tumor necrosis factor-α in MCF7 cells.

Sign Up to like & get
recommendations!
Published in 2022 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202208_29424

Abstract: OBJECTIVE Silver nanoparticles (AgNPs) are known to exhibit anti-inflammatory and anticancer activities. They have been reported to reduce the levels of tumor necrosis factor (TNF) - a proinflammatory cytokine involved in cell proliferation, differentiation, and… read more here.

Keywords: necrosis factor; agnps tfg; tumor necrosis; silver nanoparticles ... See more keywords