Anti-Neuroinflammatory Effects of a Semi-Synthetic Isoorientin-Based Glycogen Synthase Kinase-3β Inhibitor in Lipopolysaccharide-Activated Microglial Cells.
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DOI: 10.1021/acschemneuro.1c00537
Abstract: Neuroinflammation contributes to the pathogenesis of several neurodegenerative disorders. Glycogen synthase kinase-3β (GSK-3β) regulates the release of proinflammatory cytokines and promotes inflammatory responses in immune cells. Microglia are the resident mononuclear immune cells of the… read more here.
Keywords: synthase kinase; anti neuroinflammatory; glycogen synthase; microglial cells ... See more keywords