Decreased expression of circulating Aire and increased Tfh/Tfr cells in myasthenia gravis patients
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20180096
Abstract: Myasthenia gravis (MG) is a rare prototypical autoimmune disorder caused by antibodies (Ab) against postsynaptic membrane proteins. Most reports have investigated the role of autoimmune regulator gene (Aire) in thymic tissue in machianism of MG… read more here.
Keywords: aire; circulating aire; tfh tfr; expression ... See more keywords
Imbalance of Circulatory T Follicular Helper and T Follicular Regulatory Cells in Patients with ANCA-Associated Vasculitis
Sign Up to like & getrecommendations! Published in 2019 at "Mediators of Inflammation"
DOI: 10.1155/2019/8421479
Abstract: Antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) is characterized by small-vessel inflammation in association with autoantibodies. Balance between T follicular helper (Tfh) cells and T follicular regulatory (Tfr) cells is critical for humoral immune responses.… read more here.
Keywords: follicular helper; tfh tfr; associated vasculitis; tfr ... See more keywords
Inflammatory Cytokine-Neutralizing Antibody Treatment Prevented Increases in Follicular Helper T Cells and Follicular Regulatory T Cells in a Mouse Model of Arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s355720
Abstract: Background Follicular T helper (TFH) and follicular regulatory T (TFR) cells play important roles in humoral immunity. Nevertheless, their significance in rheumatoid arthritis (RA) pathogenesis has not been fully elucidated. As an important treatment strategy,… read more here.
Keywords: treatment; antibody treatment; tfh tfr; tfr cells ... See more keywords