Promoter Recognition: Putting TFIID on the Spot.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2019.06.004
Abstract: Basal transcription factor TFIID connects transcription activation to the assembly of the RNA polymerase II preinitiation complex at the core promoter of genes. The mechanistic understanding of TFIID function and dynamics has been limited by… read more here.
Keywords: promoter recognition; recognition putting; tfiid spot; tfiid ... See more keywords
TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-024-02017-z
Abstract: TFIID, one of the general transcription factor (GTF), regulates transcriptional initiation of protein-coding genes through direct binding to promoter elements and subsequent recruitment of other GTFs and RNA polymerase II. Although generally required for most… read more here.
Keywords: coding genes; protein coding; subset protein; tfiid ... See more keywords
TFIID dependency of steady-state mRNA transcription altered epigenetically by simultaneous functional loss of Taf1 and Spt3 is Hsp104-dependent
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281233
Abstract: In Saccharomyces cerevisiae, class II gene promoters have been divided into two subclasses, TFIID- and SAGA-dominated promoters or TFIID-dependent and coactivator-redundant promoters, depending on the experimental methods used to measure mRNA levels. A prior study… read more here.
Keywords: taf1; spt3; tfiid; transcription ... See more keywords