Trifluoperazine Elevates Intracellular Ca2+ Levels and Locks Open the Store‐Operated Calcium Entry Channels in Astrocytes
Sign Up to like & getrecommendations! Published in 2025 at "Glia"
DOI: 10.1002/glia.70052
Abstract: Trifluoperazine (TFP), a known inhibitor of Ca2+‐bound calmodulin (Ca2+/CaM), has been reported to elevate cytosolic Ca2+ levels by disinhibiting inositol 1,4,5‐triphosphate receptor 2 (IP3R2), thereby suppressing glioblastoma invasion and inducing apoptosis. Interestingly, TFP induces a… read more here.
Keywords: ca2 levels; store operated; ca2; sustained ca2 ... See more keywords
Enhanced Hydrophilicity of DAAQ-TFP COFs via Sulfonate Modification for Air Water Harvesting in Arid Environment.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202406803
Abstract: The poor ability of covalent organic frameworks (COFs) based adsorbents at low relative humidity (RH) conditions limits their applications for air-water harvesting in arid environments. In the present work, the sulfonated COFs (DAAQ-TFP-SO3H@LiCl) composites are… read more here.
Keywords: air water; water; daaq tfp; water harvesting ... See more keywords
Reflective functioning and its potential to moderate the efficacy of manualized psychodynamic therapies versus other treatments for borderline personality disorder.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of consulting and clinical psychology"
DOI: 10.1037/ccp0000760
Abstract: BACKGROUND Impaired reflective functioning (RF) is common among patients with borderline personality disorder (BPD). Transference-focused psychotherapy (TFP) has been demonstrated to improve RF compared to other common BPD treatments. If RF reflects a treatment mechanism… read more here.
Keywords: borderline personality; manualized psychodynamic; personality disorder; tfp ... See more keywords
A Fluorous Phosphate for the Effective Extraction of LnIII from Nitrate Media: Comparison with A Conventional Organic Phosphate
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DOI: 10.1080/07366299.2021.1874115
Abstract: ABSTRACT We compare the extraction and separation performance of a newly developed fluorous extractant, tris(4,4,5,5,6,6,7,7,7-nonafluoroheptyl) phosphate (TFP) in a fluorinated diluent perfluorohexane, for trivalent lanthanide ions (LnIII) with a conventional organic extractant, tri-n-butyl phosphate (TBP)… read more here.
Keywords: extraction; phase; tfp; separation ... See more keywords
Surface-Induced cAMP Signaling Requires Multiple Features of the Pseudomonas aeruginosa Type IV Pili
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00186-22
Abstract: Surface sensing by P. aeruginosa requires TFP. TFP plays a critical role in the induction of the second messenger cAMP upon surface contact; this second messenger is part of a larger cascade involved in the… read more here.
Keywords: camp; surface; second messenger; tfp ... See more keywords
Global Regulatory Pathways Converge To Control Expression of Pseudomonas aeruginosa Type IV Pili
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DOI: 10.1128/mbio.03696-21
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen responsible for a wide range of infections. An extensive repertoire of virulence factors aid in P. aeruginosa pathogenesis. ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa relies upon type IV pili… read more here.
Keywords: type pili; expression; tfp biogenesis; surface ... See more keywords
Health and total factor productivity nexus in selected sub-Saharan African countries: quadratic and threshold modelling
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DOI: 10.1136/bmjopen-2022-066970
Abstract: Objectives The sub-Saharan African (SSA) countries have been recording a decline in total factor productivity (TFP) growth, inadequate health funding and poor health outcomes are regarded as problems that might have impeded productivity in the… read more here.
Keywords: health; saharan african; relationship; tfp ... See more keywords
Comparison of the effectiveness of transversalis fascia plane block and transversus abdominis plane block for postoperative analgesia in pediatric lower abdominal surgeries: prospective, single blinded study
Sign Up to like & getrecommendations! Published in 2025 at "BMC Anesthesiology"
DOI: 10.1186/s12871-025-03023-z
Abstract: Achieving adequate postoperative analgesia in the pediatric age group is also important in terms of future pain perception and chronic pain development in the subsequent period. The primary aim of our study was to compare… read more here.
Keywords: plane; plane block; study; tfp ... See more keywords
Markov state modelling reveals heterogeneous drug-inhibition mechanism of Calmodulin
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DOI: 10.1371/journal.pcbi.1010583
Abstract: Calmodulin (CaM) is a calcium sensor which binds and regulates a wide range of target-proteins. This implicitly enables the concentration of calcium to influence many downstream physiological responses, including muscle contraction, learning and depression. The… read more here.
Keywords: calcium; tfp; cam; drug ... See more keywords
COX-2 Acts as a Key Mediator of Trifluoperazine-induced Cell Death in U87MG Glioma Cells
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DOI: 10.21873/anticanres.16084
Abstract: Background/Aim: Glioblastoma multiforme (GBM) is one of the most common brain tumors with a poor prognosis. Previously, we reported that trifluoperazine (TFP), a well-known antipsychotic, has anti-glioma activity through the modulation of intracellular calcium levels.… read more here.
Keywords: cell; cells cox; u87mg glioma; glioma cells ... See more keywords
Productivity and Trade Openness: A Sectoral Analysis of Morocco’s Economy
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DOI: 10.2478/eoik-2025-0052
Abstract: Abstract This study investigates the impact of trade openness and specialization on sectoral Total Factor Productivity (TFP) in Morocco from 1998 to 2018, shedding light on the intricate dynamics of the trade-productivity nexus. By adopting… read more here.
Keywords: trade; term; morocco; tfp ... See more keywords