Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease
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DOI: 10.1002/eji.202249862
Abstract: The adaptive immune response of celiac disease (CeD) involves presentation of gluten peptides to CD4+ T cells by transglutaminase 2 (TG2) specific B cells. This B‐cell/T‐cell crosstalk is facilitated by involvement of TG2:gluten peptide complexes… read more here.
Keywords: gluten peptides; celiac disease; specific cells; tg2 specific ... See more keywords