Relationships between the serum TPOAb and TGAb antibody distributions and water iodine concentrations, thyroid hormones and thyroid diseases: a cross-sectional study of 2503 adults in China
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DOI: 10.1017/s0007114522002367
Abstract: Abstract The aim of this study was to explore the status of thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in three areas with differing water iodine concentrations; and to discuss the relationships between these… read more here.
Keywords: water iodine; tgab; iodine concentrations; three areas ... See more keywords
Thyroglobulin Assay Interferences: Clinical Usefulness of Mass-Spectrometry Methods
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DOI: 10.1210/jendso/bvac169
Abstract: Abstract Context Thyroglobulin autoantibodies (TgAbs) affect thyroglobulin immunometric assays (TgIMAs), causing falsely low results. Conversely, heterophilic antibodies (HAs) may cause falsely elevated results. Thyroglobulin (Tg) measurements by mass spectrometry (MS) resist antibody interference. The most… read more here.
Keywords: mass spectrometry; tgima tgms; tgms; tgab ... See more keywords
The Presence of Serum TgAb Suggests Lower Risks for Glucose and Lipid Metabolic Disorders in Euthyroid General Population From a National Survey
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DOI: 10.3389/fendo.2020.00139
Abstract: Purpose: The expressions of antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) are very common in the sera of patients with autoimmune thyroid diseases (AITD). The relationship between thyroid autoantibodies and the occurrence of glucose… read more here.
Keywords: glucose lipid; tgab; serum tgab; tpoab tgab ... See more keywords
Clinical profiling of TPOAb and TGAb in patients with thyrotrophin receptor antibody-negative thyroid eye disease: A single-center observational study in China
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DOI: 10.3389/fendo.2025.1655598
Abstract: Background Thyrotrophin receptor antibody (TRAb)-negative thyroid eye disease (TED) constitutes a clinically significant subset of TED, yet its features remain inadequately characterized. This study characterizes the clinical features of TRAb-negative TED patients. Methods In this… read more here.
Keywords: thyrotrophin receptor; trab negative; tpoab tgab; tgab ... See more keywords
Autoimmune thyroid disease modifies the clinical expression of hand osteoarthritis in older people: a third National Health and nutrition examination survey study
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DOI: 10.3389/fmed.2024.1445188
Abstract: Introduction The risk factors linked to hand osteoarthritis (OA) that contribute to its distinct symptoms and clinical presentation are not thoroughly understood. This study aimed to examine whether the autoimmune thyroid disease (AITD) autoantibodies, anti-thyroid… read more here.
Keywords: hand; hand osteoarthritis; thyroid disease; symptomatic hand ... See more keywords
Clinical Utility of Liquid Chromatography-Tandem Mass Spectrometry for Thyroglobulin Measurement in Comparison with Immunoradiometric Assay and Chemiluminescence Microparticle Immunoassay.
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DOI: 10.3803/enm.2025.2413
Abstract: Background The liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to overcome interference from thyroglobulin autoantibodies (TgAb); however, it has not yet been implemented in Korea. This study aimed to confirm the accuracy of LC-MS/MS… read more here.
Keywords: tandem mass; mass spectrometry; tgab; cmia ... See more keywords