Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain
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DOI: 10.1007/s11064-017-2286-9
Abstract: The series of experiments herein evaluated prototype drugs representing different mechanisms of antiseizure, antinociceptive or antidepressant action in a battery of preclinical pain models in adult male CF#1 mice (formalin, writhing, and tail flick) and… read more here.
Keywords: antinociceptive antidepressant; antiseizure antinociceptive; mor; tgb ... See more keywords
Human Serum Albumin-Occupying-Based Fluorescence Turn-On Analysis of Anti-epileptic Drug Tiagabine Hydrochloride.
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DOI: 10.1021/acs.analchem.9b03507
Abstract: Tiagabine hydrochloride (TGB) is a clinically frequently-used drug for anti-convulsion and reducing epileptic frequency. Over administration of TGB could bring about adverse effects, such as speech disorder, depression and even suicidal tendencies. Therefore, accessible and… read more here.
Keywords: tgb; drug; human serum; fluorescence turn ... See more keywords