The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling
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DOI: 10.1016/j.taap.2018.07.028
Abstract: &NA; Cardenolides are plant‐derived toxic substances. Their cytotoxicity and the underlying mechanistic signaling axes have been extensively documented, but only a few anti‐viral activities of cardenolides and the associated signaling pathways have been reported. Previously,… read more here.
Keywords: tgev activity; pi3k pdk1; tgev;