Myofibroblast TGF-β Activation Measurement In Vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1382-5_6
Abstract: Myofibroblasts are critical to processes involved in normal wound healing and during pathological fibrosis. They transdifferentiate from fibroblasts, and in doing so become contractile and capable of secreting large amounts of extracellular matrix proteins. Transforming… read more here.
Keywords: myofibroblast tgf; matrix; activation measurement; tgf ... See more keywords
Oscillatory shear potentiates latent TGF-β1 activation more than steady shear as demonstrated by a novel force generator
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DOI: 10.1038/s41598-019-42302-x
Abstract: Cardiovascular mechanical stresses trigger physiological and pathological cellular reactions including secretion of Transforming Growth Factor β1 ubiquitously in a latent form (LTGF-β1). While complex shear stresses can activate LTGF-β1, the mechanisms underlying LTGF-β1 activation remain… read more here.
Keywords: activation; ltgf activation; steady shear; oscillatory shear ... See more keywords
Phenytoin induces connective tissue growth factor (CTGF/CCN2) production through NADPH oxidase 4-mediated latent TGFβ1 activation in human gingiva fibroblasts: Suppression by curcumin.
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DOI: 10.1111/jre.13058
Abstract: OBJECTIVE AND BACKGROUND Gingival overgrowth (GO) is a common side effect of some drugs such as anticonvulsants, immunosuppressant, and calcium channel blockers. Among them, the antiepileptic agent phenytoin is the most common agent related to… read more here.
Keywords: ccn2 synthesis; phenytoin; latent tgf; tgf activation ... See more keywords
TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice
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DOI: 10.1371/journal.ppat.1007657
Abstract: Helminths are highly prevalent metazoan parasites that infect over a billion of the world’s population. Hosts have evolved numerous mechanisms to drive the expulsion of these parasites via Th2-driven immunity, but these responses must be… read more here.
Keywords: expulsion; trichinella spiralis; spiralis; tgf activation ... See more keywords