Ulipristal acetate decreases active TGF-β3 and its canonical signaling in uterine leiomyoma via two novel mechanisms.
Sign Up to like & getrecommendations! Published in 2019 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2018.12.026
Abstract: OBJECTIVE To characterize the effect of ulipristal acetate (UPA) treatment on transforming growth factor (TGF) canonical and noncanonical signaling pathways in uterine leiomyoma tissue and cells. UPA decreased extracellular matrix in surgical specimens; we characterize… read more here.
Keywords: active tgf; canonical signaling; tgf canonical; ulipristal acetate ... See more keywords
Association of TGF-β Canonical Signaling-Related Core Genes With Aortic Aneurysms and Aortic Dissections
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.888563
Abstract: Transforming growth factor-beta (TGF-β) signaling is essential for the maintenance of the normal structure and function of the aorta. It includes SMAD-dependent canonical pathways and noncanonical signaling pathways. Accumulated genetic evidence has shown that TGF-β… read more here.
Keywords: aortic aneurysms; tgf canonical; aortic dissections; signaling related ... See more keywords