Inorganic arsenic promotes apoptosis of human immortal keratinocytes through the TGF‐β1/ERK signaling pathway
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DOI: 10.1002/tox.23486
Abstract: Chronic exposure to high‐dose inorganic arsenic through groundwater, air, or food remains a major environmental public health issue worldwide. Apoptosis, a method of cell death, has recently become a hot topic of research in biology… read more here.
Keywords: erk signaling; tgf erk; apoptosis; signaling pathway ... See more keywords
Disulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis
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DOI: 10.2147/cmar.s199912
Abstract: Purpose: Smad4 loss is highly related to poor prognosis and decreased patient survival in oral squamous cell carcinoma (OSCC), suggesting that agents that target both Smad4-mutated and Smad4 wild-type cells could treat OSCC more effectively.… read more here.
Keywords: tgf; emt; snail; tgf erk ... See more keywords