Transcriptional repression of the tyrosinase-related protein 2 gene by transforming growth factor-β and the Kruppel-like transcription factor GLI2.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.04.001
Abstract: BACKGROUND Tyrosinase-Related Protein 2 (TRP2) is an enzyme involved in melanogenesis, that also exerts proliferative, anti-apoptotic and immunogenic functions in melanoma cells. TRP2 transcription is regulated by the melanocytic master transcription factor MITF. GLI2, a… read more here.
Keywords: gli2; factor; repression; transcription factor ... See more keywords