Microvesicles derived from TGF-β1 stimulated hepatic stellate cells aggravate hepatocellular injury.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cells and development"
DOI: 10.1089/scd.2019.0032
Abstract: Hepatic stellate cells (HSCs) are liver specific cells playing critical roles in liver physiological and pathophysiological processes. Transforming growth factor-β1 (TGF-β1) is an inflammatory cytokine secreted by both hepatocytes and HSCs. We have previously shown… read more here.
Keywords: stellate cells; hepatic stellate; injury; hsc mvs ... See more keywords
MYH9 Inhibition Suppresses TGF-β1-Stimulated Lung Fibroblast-to-Myofibroblast Differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.573524
Abstract: Previous cDNA microarray results showed that MYH9 gene expression levels are increased in TGF-β1-stimulated lung fibroblast. Recently, our proteomic results revealed that the expression levels of MYH9 protein are notably upregulated in lung tissues of… read more here.
Keywords: lung; lung fibroblast; differentiation; tgf stimulated ... See more keywords
Dietary AhR Ligands Have No Anti-Fibrotic Properties in TGF-β1-Stimulated Human Colonic Fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14163253
Abstract: Background: Intestinal fibrosis is a common complication in inflammatory bowel disease (IBD) patients without specific treatment. Aryl hydrocarbon receptor (AhR) activation is associated with better outcomes in intestinal inflammation. Development of novel therapies targeting fibrogenic… read more here.
Keywords: human colonic; dietary ahr; ahr ligands; tgf stimulated ... See more keywords