Regulation of homeostasis and regeneration in the adult intestinal epithelium by the TGF‐β superfamily
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.500
Abstract: The delicate balance between the homeostatic maintenance and regenerative capacity of the intestine makes this a fascinating tissue of study. The intestinal epithelium undergoes continuous homeostatic renewal but is also exposed to a diverse array… read more here.
Keywords: regulation homeostasis; intestinal epithelium; epithelium; adult intestinal ... See more keywords
A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.08.010
Abstract: We present an integromic analysis of gene alterations that modulate transforming growth factor β (TGF-β)-Smad-mediated signaling in 9,125 tumor samples across 33 cancer types in The Cancer Genome Atlas (TCGA). Focusing on genes that encode… read more here.
Keywords: analysis reveals; tgf superfamily; pan cancer; cancer analysis ... See more keywords
Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101426
Abstract: Summary Homeostatic generation of T cells, which occurs in the thymus, is controlled at least in part by endogenous cytokines and ligands. In addition, nutritional factors are other key regulators for the homeostasis of host… read more here.
Keywords: differentiation cells; tgf superfamily; thymic stromal; production ... See more keywords
Expression profiling of ovarian BMP antagonists reveals the potential interaction between TWSG1 and the chordin subfamily in the ovary
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2021.111457
Abstract: The TGF-β superfamily members and their antagonists comprise an indispensable system that controls mammalian ovarian development in a sophisticated manner. In contrast to a plethora of studies on the ovary-expressed TGF-β superfamily members, knowledge regarding… read more here.
Keywords: tgf superfamily; bmp antagonists; expression; superfamily members ... See more keywords
The Role of the TGF-β Superfamily in Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2019.00140
Abstract: The members of the transforming growth factor β (TGF-β) superfamily are essential regulators of cell differentiation, phenotype and function, and have been implicated in the pathogenesis of many diseases. Myocardial infarction is associated with induction… read more here.
Keywords: role tgf; tgf superfamily; myocardial infarction;
Therapeutic Approaches for Treating Pulmonary Arterial Hypertension by Correcting Imbalanced TGF-β Superfamily Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.814222
Abstract: Pulmonary arterial hypertension (PAH) is a rare disease characterized by high blood pressure in the pulmonary circulation driven by pathological remodeling of distal pulmonary arteries, leading typically to death by right ventricular failure. Available treatments… read more here.
Keywords: arterial hypertension; pulmonary arterial; pah; tgf superfamily ... See more keywords