Design, 3D QSAR modeling and docking of TGF-β type I inhibitors to target cancer
Sign Up to like & getrecommendations! Published in 2018 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2018.07.011
Abstract: Transforming growth factor-β (TGF-β) family members plays a vital role in regulating hormonal function, bone formation, tissue remodeling, and erythropoiesis, cell growth and apoptosis. TGF-β super-family members mediate signal transduction via serine/threonine kinase receptors located… read more here.
Keywords: tgf type; type inhibitors; qsar; cancer ... See more keywords
Role of human adipose-derived stem cells (hADSC) on TGF-β1, type I collagen, and fibrosis degree in bladder obstruction model of Wistar rats
Sign Up to like & getrecommendations! Published in 2022 at "BMC Urology"
DOI: 10.1186/s12894-022-01019-2
Abstract: Introduction Bladder outlet obstruction (BOO) was caused by a series of histological and biochemical changes in the bladder wall, through the inflammation process in the bladder wall, hypertrophy and fibrosis. ADSC has an important role… read more here.
Keywords: type collagen; fibrosis; wistar; tgf type ... See more keywords
A TGF-β type II receptor that associates with developmental transition in Haemonchus contortus in vitro
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007913
Abstract: Background The TGF-β signalling pathway plays a key role in regulating dauer formation in the free-living nematode Caenorhabditis elegans, and previous work has shown that TGF-β receptors are involved in parasitic nematodes. Here, we explored… read more here.
Keywords: haemonchus contortus; tgf; tgf type; type receptor ... See more keywords