TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles.
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DOI: 10.1016/j.biomaterials.2019.119544
Abstract: Mesenchymal stem/stromal cells (MSCs) are of interest in the context of osteoarthritis (OA) therapy. We previously demonstrated that TGFβ-induced gene product-h3 (TGFBI/BIGH3) is downregulated in human MSCs (hMSCs) from patients with OA, suggesting a possible… read more here.
Keywords: extracellular vesicles; secreted mesenchymal; mesenchymal stromal; cells ameliorates ... See more keywords