Articles with "tgfbr2 mediated" as a keyword



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Abstract 3430: TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-β signaling

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Published in 2019 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs18-3430

Abstract: The Ser/Thr kinase BUB1 (budding uninhibited by benzimidazoles-1) is required for efficient signaling by the TGF-β receptor. Recruitment of BUB1 to the activated heteromeric TGF-β-receptor complex including SMAD2 and SMAD3, is required for ligand mediated… read more here.

Keywords: tgfbr2 mediated; phosphorylation bub1; bub1; mediated phosphorylation ... See more keywords