Articles with "tgfbr3" as a keyword



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MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability.

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Published in 2023 at "JCI insight"

DOI: 10.1172/jci.insight.159058

Abstract: Although the expression of Mex3 RNA-binding family member B (MEX3B) is upregulated in human nasal epithelial cells (HNECs) predominately in the eosinophilic chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) subtype, its functions as an RNA… read more here.

Keywords: nasal polyps; collagen; eosinophilic crswnp; tgfbr3 ... See more keywords
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TGFBR3 supports anoikis through suppressing ATF4 signaling.

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Published in 2022 at "Journal of cell science"

DOI: 10.1242/jcs.258396

Abstract: Epithelial morphogenesis and oncogenic transformation can cause loss of cell adhesion, and detached cells are eliminated by anoikis. Here, we reveal that transforming growth factor beta receptor 3 (TGFBR3) acts as an anoikis mediator through… read more here.

Keywords: atf4 signaling; supports anoikis; suppressing atf4; anoikis suppressing ... See more keywords
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Promoter Hypomethylation of TGFBR3 as a Risk Factor of Alzheimer’s Disease: An Integrated Epigenomic-Transcriptomic Analysis

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.825729

Abstract: Alzheimer’s disease (AD) is characterized by the abnormal deposition of amyloid-β (Aβ) plaques and tau tangles in the brain and accompanied with cognitive impairment. However, the fundamental cause of this disease remains elusive. To elucidate… read more here.

Keywords: tgfbr3; analysis; alzheimer disease; tgfbr3 risk ... See more keywords