Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning
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DOI: 10.1038/ejhg.2016.164
Abstract: Holoprosencephaly (HPE) is a prevalent craniofacial developmental disorder that has both genetic and environmental causes. The gene encoding TG-interacting factor 1 (TGIF1) is among those that are routinely screened in HPE patients. However, the mechanisms… read more here.
Keywords: genetic molecular; independent effects; hpe; tgifs nodal ... See more keywords