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Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00087
Abstract: 3-Thiaglutamate is a recently identified amino acid analog originating from cysteine. During its biosynthesis, cysteinyl-tRNA is first enzymatically appended to the C-terminus of TglA, a 50-residue ribosomally translated peptide scaffold. After hydrolytic removal of the…
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Keywords:
biosynthesis;
recognition peptidyl;
tglhi;
substrate recognition ... See more keywords