Th1 cytokines, true functional signatures for protective immunity against TB?
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DOI: 10.1038/cmi.2017.113
Abstract: The lack of an effective preventative vaccine against tuberculosis (TB) presents a great challenge to TB control. Since it takes an extremely long time to accurately determine the protective efficacy of TB vaccines, there is… read more here.
Keywords: functional signatures; vaccine; signatures protective; th1 cytokines ... See more keywords
Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer
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DOI: 10.1155/2021/8818393
Abstract: Although immune-based therapies have made remarkable inroads in cancer treatment, they usually must be combined with standard treatment modalities, including cytotoxic drugs, to achieve maximal clinical benefits. As immunotherapies are further advanced and refined, considerable… read more here.
Keywords: breast; sunitinib; breast cancer; cancer cells ... See more keywords
Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis
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DOI: 10.3390/ijms22083806
Abstract: In Hashimoto’s thyroiditis (HT), oxidative stress (OS) is driven by Th1 cytokines’ response interfering with the normal function of thyrocytes. OS results from an imbalance between an excessive production of reactive oxygen species (ROS) and… read more here.
Keywords: glut vegf; hashimoto thyroiditis; hif glut; th1 cytokines ... See more keywords